Induction of p53-Independent Apoptosis by the Adenovirus E4orf4 Protein Requires Binding to the Bα Subunit of Protein Phosphatase 2A

Previous studies have indicated that the E4orf4 protein of human adenovirus type 2 (Ad2) induces p53-independent apoptosis. We believe that this process may play a role in cell death and viral spread at the final stages of productive infection. E4orf4 may also be of therapeutic value in treating som...

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Publié dans:	J Virol
Auteurs principaux:	Marcellus, Richard C., Chan, Helen, Paquette, Denis, Thirlwell, Sarah, Boivin, Dominique, Branton, Philip E.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2000
Sujets:	Virus-Cell Interactions
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112317/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10933694/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.17.7869-7877.2000
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