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Effects of Amino Acid Substitutions at Position 115 on the Fidelity of Human Immunodeficiency Virus Type 1 Reverse Transcriptase

We compared the fidelity of wild-type human immunodeficiency virus type-1 (HIV-1) reverse transcriptase (RT) and two RT mutants, Y115F and Y115V. Although neither mutation had a large effect on the overall fidelity of the enzyme, both mutations altered the spectrum of mutations and the precise natur...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Boyer, Paul L., Hughes, Stephen H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC112158/
https://ncbi.nlm.nih.gov/pubmed/10864662
Tagiau: Ychwanegu Tag
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