A Rev-Independent Human Immunodeficiency Virus Type 1 (HIV-1)-Based Vector That Exploits a Codon-Optimized HIV-1 gag-pol Gene

The human immunodeficiency virus (HIV) genome is AU rich, and this imparts a codon bias that is quite different from the one used by human genes. The codon usage is particularly marked for the gag, pol, and env genes. Interestingly, the expression of these genes is dependent on the presence of the R...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Kotsopoulou, Ekaterini, Kim, V. Narry, Kingsman, Alan J., Kingsman, Susan M., Mitrophanous, Kyriacos A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Gene Therapy
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112007/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10775623/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.10.4839-4852.2000
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