A Rev-Independent Human Immunodeficiency Virus Type 1 (HIV-1)-Based Vector That Exploits a Codon-Optimized HIV-1 gag-pol Gene

The human immunodeficiency virus (HIV) genome is AU rich, and this imparts a codon bias that is quite different from the one used by human genes. The codon usage is particularly marked for the gag, pol, and env genes. Interestingly, the expression of these genes is dependent on the presence of the R...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kotsopoulou, Ekaterini, Kim, V. Narry, Kingsman, Alan J., Kingsman, Susan M., Mitrophanous, Kyriacos A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112007/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10775623/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.10.4839-4852.2000
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