A Single Intramuscular Injection of Recombinant Plasmid DNA Induces Protective Immunity and Prevents Japanese Encephalitis in Mice

Plasmid vectors containing Japanese encephalitis virus (JEV) premembrane (prM) and envelope (E) genes were constructed that expressed prM and E proteins under the control of a cytomegalovirus immediate-early gene promoter. COS-1 cells transformed with this plasmid vector (JE-4B clone) secreted JEV-s...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Chang, Gwong-Jen J., Hunt, Ann R., Davis, Brent
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2000
Assuntos:	Vaccines and Antiviral Agents
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111940/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10756038/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.9.4244-4252.2000
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