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A Single Intramuscular Injection of Recombinant Plasmid DNA Induces Protective Immunity and Prevents Japanese Encephalitis in Mice

Plasmid vectors containing Japanese encephalitis virus (JEV) premembrane (prM) and envelope (E) genes were constructed that expressed prM and E proteins under the control of a cytomegalovirus immediate-early gene promoter. COS-1 cells transformed with this plasmid vector (JE-4B clone) secreted JEV-s...

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Pubblicato in:J Virol
Autori principali: Chang, Gwong-Jen J., Hunt, Ann R., Davis, Brent
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111940/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10756038/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.9.4244-4252.2000
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