A Single Intramuscular Injection of Recombinant Plasmid DNA Induces Protective Immunity and Prevents Japanese Encephalitis in Mice

Plasmid vectors containing Japanese encephalitis virus (JEV) premembrane (prM) and envelope (E) genes were constructed that expressed prM and E proteins under the control of a cytomegalovirus immediate-early gene promoter. COS-1 cells transformed with this plasmid vector (JE-4B clone) secreted JEV-s...

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Publié dans:	J Virol
Auteurs principaux:	Chang, Gwong-Jen J., Hunt, Ann R., Davis, Brent
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2000
Sujets:	Vaccines and Antiviral Agents
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111940/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10756038/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.9.4244-4252.2000
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