Transgenic mice support replication of hepatitis delta virus RNA in multiple tissues, particularly in skeletal muscle.

Hepatitis delta virus (HDV) is hepatotropic and frequently causes fulminant hepatitis in both human and nonhuman primate hosts. To understand the molecular basis of HDV tissue tropism and the mechanism of pathogenesis, transgenic mice in which replication-competent HDV dimeric RNA is expressed under...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Polo, J M, Jeng, K S, Lim, B, Govindarajan, S, Hofman, F, Sangiorgi, F, Lai, M M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189302/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7609056/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.8.4880-4887.1995
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