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Transgenic mice support replication of hepatitis delta virus RNA in multiple tissues, particularly in skeletal muscle.

Hepatitis delta virus (HDV) is hepatotropic and frequently causes fulminant hepatitis in both human and nonhuman primate hosts. To understand the molecular basis of HDV tissue tropism and the mechanism of pathogenesis, transgenic mice in which replication-competent HDV dimeric RNA is expressed under...

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Publikašuvnnas:J Virol
Váldodahkkit: Polo, J M, Jeng, K S, Lim, B, Govindarajan, S, Hofman, F, Sangiorgi, F, Lai, M M
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: American Society for Microbiology (ASM) 1995
Fáttát:
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189302/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7609056/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.8.4880-4887.1995
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