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Herpesvirus mRNAs Are Sorted for Export via Crm1-Dependent and -Independent Pathways

Cellular pre-mRNA splicing is inhibited by ICP27, a herpes simplex virus regulatory protein, resulting in the shutoff of host protein synthesis. Here we reveal that ICP27 also mediates the export of some virus RNAs via a Crm1-dependent pathway and present evidence that independent domains are requir...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Soliman, Tarik M., Silverstein, Saul J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2000
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111772/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10684298/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.6.2814-2825.2000
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