SUN5, a testis-specific nuclear membrane protein, participates in recruitment and export of nuclear mRNA in spermatogenesis
SUN5, a testis-specific gene, is associated with acephalic spermatozoa syndrome (ASS). Here, we demonstrate that SUN5 is involved in mRNA export. In Sun5-knockout mice (Sun5<sup>–/–</sup>), poly(A)<sup>+</sup> RNA accumulates in the nuclei of germ cells, leading to reduced sperm counts, decreased sp...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
China Science Publishing & Media Ltd.
2024-08-01
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| Serie: | Acta Biochimica et Biophysica Sinica |
| Soggetti: | |
| Accesso online: | https://www.sciengine.com/doi/10.3724/abbs.2024134 |
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