SUN5, a testis-specific nuclear membrane protein, participates in recruitment and export of nuclear mRNA in spermatogenesis

SUN5, a testis-specific gene, is associated with acephalic spermatozoa syndrome (ASS). Here, we demonstrate that SUN5 is involved in mRNA export. In Sun5-knockout mice (Sun5^–/–), poly(A)⁺ RNA accumulates in the nuclei of germ cells, leading to reduced sperm counts, decreased sp...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	He Xiyi, Zhang Yunfei, Mao Zenghui, Liu Gang, Huang Lihua, Liu Xiaowen, Su Yuyan, Xing Xiaowei
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	China Science Publishing & Media Ltd. 2024-08-01
Цуврал:	Acta Biochimica et Biophysica Sinica
Нөхцлүүд:	SUN5 hnRNPs Nup93 Nxf1 mRNA export
Онлайн хандалт:	https://www.sciengine.com/doi/10.3724/abbs.2024134
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!