Herpesvirus mRNAs Are Sorted for Export via Crm1-Dependent and -Independent Pathways
Cellular pre-mRNA splicing is inhibited by ICP27, a herpes simplex virus regulatory protein, resulting in the shutoff of host protein synthesis. Here we reveal that ICP27 also mediates the export of some virus RNAs via a Crm1-dependent pathway and present evidence that independent domains are requir...
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| Опубликовано в:: | J Virol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111772/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10684298/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.6.2814-2825.2000 |
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