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Herpesvirus mRNAs Are Sorted for Export via Crm1-Dependent and -Independent Pathways

Cellular pre-mRNA splicing is inhibited by ICP27, a herpes simplex virus regulatory protein, resulting in the shutoff of host protein synthesis. Here we reveal that ICP27 also mediates the export of some virus RNAs via a Crm1-dependent pathway and present evidence that independent domains are requir...

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Detalhes bibliográficos
Main Authors: Soliman, Tarik M., Silverstein, Saul J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111772/
https://ncbi.nlm.nih.gov/pubmed/10684298
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