Efficient Gene Transfer into Human CD34(+) Cells by a Retargeted Adenovirus Vector
Efficient infection with adenovirus (Ad) vectors based on serotype 5 (Ad5) requires the presence of coxsackievirus-adenovirus receptors (CAR) and α(v) integrins on cells. The paucity of these cellular receptors is thought to be a limiting factor for Ad gene transfer into hematopoietic stem cells. In...
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| Gepubliceerd in: | J Virol |
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| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology (ASM)
2000
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10684271/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.6.2567-2583.2000 |
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