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Prophylactic and Therapeutic Benefits of Short-Term 9-[2-(R)-(Phosphonomethoxy)Propyl]Adenine (PMPA) Administration to Newborn Macaques following Oral Inoculation with Simian Immunodeficiency Virus with Reduced Susceptibility to PMPA

Simian immunodeficiency virus (SIV) infection of newborn macaques is a useful animal model of human pediatric AIDS to study pathogenesis and to develop intervention strategies aimed at preventing infection or delaying disease progression. In previous studies, we demonstrated that 9-[2-(R)-(phosphono...

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Udgivet i:J Virol
Principais autores: Van Rompay, Koen K. A., Miller, Michael D., Marthas, Marta L., Margot, Nicolas A., Dailey, Peter J., Canfield, Don R., Tarara, Ross P., Cherrington, Julie M., Aguirre, Nancy L., Bischofberger, Norbert, Pedersen, Niels C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111653/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10644348/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.4.1767-1774.2000
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