Prophylactic and Therapeutic Benefits of Short-Term 9-[2-(R)-(Phosphonomethoxy)Propyl]Adenine (PMPA) Administration to Newborn Macaques following Oral Inoculation with Simian Immunodeficiency Virus with Reduced Susceptibility to PMPA

Simian immunodeficiency virus (SIV) infection of newborn macaques is a useful animal model of human pediatric AIDS to study pathogenesis and to develop intervention strategies aimed at preventing infection or delaying disease progression. In previous studies, we demonstrated that 9-[2-(R)-(phosphono...

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Détails bibliographiques
Auteurs principaux: Van Rompay, Koen K. A., Miller, Michael D., Marthas, Marta L., Margot, Nicolas A., Dailey, Peter J., Canfield, Don R., Tarara, Ross P., Cherrington, Julie M., Aguirre, Nancy L., Bischofberger, Norbert, Pedersen, Niels C.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC111653/
https://ncbi.nlm.nih.gov/pubmed/10644348
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