pRB-Dependent, J Domain-Independent Function of Simian Virus 40 Large T Antigen in Override of p53 Growth Suppression
Simian virus 40 (SV40) large T antigen (LT) can immortalize and transform many cell types. These activities are attributed in large part to the binding and functional inactivation by LT of two major tumor suppressors: p53 and the retinoblastoma protein, pRB. Most effects of LT on pRB have been shown...
Guardado en:
| Publicado en: | J Virol |
|---|---|
| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2000
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111607/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10623749/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.2.864-874.2000 |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|