De Novo Initiation of RNA Synthesis by the RNA-Dependent RNA Polymerase (NS5B) of Hepatitis C Virus

Hepatitis C virus (HCV) NS5B protein possesses an RNA-dependent RNA polymerase (RdRp) activity, a major function responsible for replication of the viral RNA genome. To further characterize the RdRp activity, NS5B proteins were expressed from recombinant baculoviruses, purified to near homogeneity,...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Luo, Guangxiang, Hamatake, Robert K., Mathis, Danielle M., Racela, Jason, Rigat, Karen L., Lemm, Julie, Colonno, Richard J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111606/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10623748/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.2.851-863.2000
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