De Novo Initiation of RNA Synthesis by the RNA-Dependent RNA Polymerase (NS5B) of Hepatitis C Virus

Hepatitis C virus (HCV) NS5B protein possesses an RNA-dependent RNA polymerase (RdRp) activity, a major function responsible for replication of the viral RNA genome. To further characterize the RdRp activity, NS5B proteins were expressed from recombinant baculoviruses, purified to near homogeneity,...

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Autores principales: Luo, Guangxiang, Hamatake, Robert K., Mathis, Danielle M., Racela, Jason, Rigat, Karen L., Lemm, Julie, Colonno, Richard J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
Materias:
Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC111606/
https://ncbi.nlm.nih.gov/pubmed/10623748
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