Entry versus Blockade of Brain Infection following Oral or Intraperitoneal Scrapie Administration: Role of Prion Protein Expression in Peripheral Nerves and Spleen

Naturally occurring transmissible spongiform encephalopathy (TSE) diseases such as bovine spongiform encephalopathy in cattle are probably transmitted by oral or other peripheral routes of infection. While prion protein (PrP) is required for susceptibility, the mechanism of spread of infection to th...

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Bibliographic Details
Main Authors: Race, Richard, Oldstone, Michael, Chesebro, Bruce
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC111603/
https://ncbi.nlm.nih.gov/pubmed/10623745
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