Reduction of GC → TA Transversion Mutation by Overexpression of MutS in Escherichia coli K-12

Overexpression of the MutS repair protein significantly decreased the rate of lacZ GC → TA transversion mutation in stationary-phase and exponentially growing bacteria and in mutY and mutM mutants, which accumulate mismatches between 8-oxoguanine (8-oxoG) and adenine residues in DNA. Conversely, GC...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Zhao, Jingyong, Winkler, Malcolm E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Genetics and Molecular Biology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111390/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10940054/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.17.5025-5028.2000
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