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Viral Expression of CCL2 Is Sufficient To Induce Demyelination in RAG1(−/−) Mice Infected with a Neurotropic Coronavirus

Mouse hepatitis virus strain JHM causes a chronic demyelinating disease in susceptible strains of rodents. Demyelination does not develop in infected RAG1(−/−) (recombination activation gene-deficient) mice but can be induced by several experimental interventions, including adoptive transfer of viru...

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Detalhes bibliográficos
Main Authors: Kim, Taeg S., Perlman, Stanley
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1112157/
https://ncbi.nlm.nih.gov/pubmed/15890951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.11.7113-7120.2005
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