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Virus-Specific Antibody, in the Absence of T Cells, Mediates Demyelination in Mice Infected with a Neurotropic Coronavirus

Mice infected with mouse hepatitis virus strain JHM develop an inflammatory demyelinating disease in the central nervous system with many similarities to human multiple sclerosis. The mouse disease is primarily immune-mediated because demyelination is not detected in JHM-infected mice lacking T or B...

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Hlavní autoři: Kim, Taeg S., Perlman, Stanley
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602352/
https://ncbi.nlm.nih.gov/pubmed/15743792
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