Strategy for Systematic Assembly of Large RNA and DNA Genomes: Transmissible Gastroenteritis Virus Model

A systematic method was developed to assemble functional full-length genomes of large RNA and DNA viruses. Coronaviruses contain the largest single-stranded positive-polarity RNA genome in nature. The ∼30-kb genome, coupled with regions of genomic instability, has hindered the development of a full-...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Yount, Boyd, Curtis, Kristopher M., Baric, Ralph S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2000
Ämnen:
Replication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC110934/
https://ncbi.nlm.nih.gov/pubmed/11044104
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