Strategy for Systematic Assembly of Large RNA and DNA Genomes: Transmissible Gastroenteritis Virus Model

A systematic method was developed to assemble functional full-length genomes of large RNA and DNA viruses. Coronaviruses contain the largest single-stranded positive-polarity RNA genome in nature. The ∼30-kb genome, coupled with regions of genomic instability, has hindered the development of a full-...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Yount, Boyd, Curtis, Kristopher M., Baric, Ralph S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110934/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11044104/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.22.10600-10611.2000
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