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Strategy for Systematic Assembly of Large RNA and DNA Genomes: Transmissible Gastroenteritis Virus Model

A systematic method was developed to assemble functional full-length genomes of large RNA and DNA viruses. Coronaviruses contain the largest single-stranded positive-polarity RNA genome in nature. The ∼30-kb genome, coupled with regions of genomic instability, has hindered the development of a full-...

Täydet tiedot

Tallennettuna:
Julkaisussa:J Virol
Päätekijät: Yount, Boyd, Curtis, Kristopher M., Baric, Ralph S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2000
Aiheet:
Replication
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110934/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11044104/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.22.10600-10611.2000
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