The ETO Protein Disrupted in t(8;21)-Associated Acute Myeloid Leukemia Is a Corepressor for the Promyelocytic Leukemia Zinc Finger Protein

The ETO protein was originally identified by its fusion to the AML-1 transcription factor in translocation (8;21) associated with the M2 form of acute myeloid leukemia (AML). The resulting AML-1–ETO fusion is an aberrant transcriptional regulator due to the ability of ETO, which does not bind DNA it...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Melnick, Ari M., Westendorf, Jennifer J., Polinger, Adam, Carlile, Graeme W., Arai, Sally, Ball, Helen J., Lutterbach, Bart, Hiebert, Scott W., Licht, Jonathan D.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2000
Sujets:	Transcriptional Regulation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110824/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688654/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.6.2075-2086.2000
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