The ETO Protein Disrupted in t(8;21)-Associated Acute Myeloid Leukemia Is a Corepressor for the Promyelocytic Leukemia Zinc Finger Protein
The ETO protein was originally identified by its fusion to the AML-1 transcription factor in translocation (8;21) associated with the M2 form of acute myeloid leukemia (AML). The resulting AML-1–ETO fusion is an aberrant transcriptional regulator due to the ability of ETO, which does not bind DNA it...
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| I publikationen: | Mol Cell Biol |
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| Huvudupphov: | , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Taylor & Francis
2000
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110824/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688654/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.6.2075-2086.2000 |
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