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BSAP Can Repress Enhancer Activity by Targeting PU.1 Function

PU.1 and BSAP are transcription factors crucial for proper B-cell development. Absence of PU.1 results in loss of B, T, and myeloid cells, while absence of BSAP results in an early block in B-cell differentiation. Both of these proteins bind to the immunoglobulin κ chain 3′ enhancer, which is develo...

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Sonraí Bibleagrafaíochta
Main Authors: Maitra, Shanak, Atchison, Michael
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2000
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC110809/
https://ncbi.nlm.nih.gov/pubmed/10688639
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