BSAP Can Repress Enhancer Activity by Targeting PU.1 Function
PU.1 and BSAP are transcription factors crucial for proper B-cell development. Absence of PU.1 results in loss of B, T, and myeloid cells, while absence of BSAP results in an early block in B-cell differentiation. Both of these proteins bind to the immunoglobulin κ chain 3′ enhancer, which is develo...
Gespeichert in:
| Veröffentlicht in: | Mol Cell Biol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110809/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.6.1911-1922.2000 |
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