BSAP Can Repress Enhancer Activity by Targeting PU.1 Function

PU.1 and BSAP are transcription factors crucial for proper B-cell development. Absence of PU.1 results in loss of B, T, and myeloid cells, while absence of BSAP results in an early block in B-cell differentiation. Both of these proteins bind to the immunoglobulin κ chain 3′ enhancer, which is develo...

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Detaylı Bibliyografya
Asıl Yazarlar: Maitra, Shanak, Atchison, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2000
Konular:
Transcriptional Regulation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC110809/
https://ncbi.nlm.nih.gov/pubmed/10688639
Etiketler: Etiketle
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