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BSAP Can Repress Enhancer Activity by Targeting PU.1 Function

PU.1 and BSAP are transcription factors crucial for proper B-cell development. Absence of PU.1 results in loss of B, T, and myeloid cells, while absence of BSAP results in an early block in B-cell differentiation. Both of these proteins bind to the immunoglobulin κ chain 3′ enhancer, which is develo...

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Udgivet i:Mol Cell Biol
Principais autores: Maitra, Shanak, Atchison, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2000
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110809/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688639/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.6.1911-1922.2000
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