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Expansion of the (CTG)(n) repeat in the 5′-UTR of a reporter gene impedes translation
Effects of d(CAG)(n)·d(CTG)(n) repeats on expression of a reporter gene in human cell culture were studied using transient transfection, RNase protection and coupled transcription/translation assays. Cloning these repeats into the reporter 3′-UTR did not affect gene functioning. In contrast, placing...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2000
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC110791/ https://ncbi.nlm.nih.gov/pubmed/11024174 |
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