p53 C-terminal interaction with DNA ends and gaps has opposing effect on specific DNA binding by the core
In addition to binding DNA in a sequence-specific manner, the p53 tumour suppressor protein can interact with damaged DNA. In order to understand which structural features in DNA the C-teminal domain recognises we have studied the interaction of p53 protein with different types of DNA oligonucleotid...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110788/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11024181/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.20.4005 |
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