p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

The p53 tumor-suppressor protein has previously been shown to bind double-stranded and single-stranded DNA. We report that the p53 protein can bind single-stranded DNA ends and catalyze DNA renaturation and DNA strand transfer. Both a bacterially expressed wild-type p53 protein and a glutathione S-t...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Bakalkin, G, Yakovleva, T, Selivanova, G, Magnusson, K P, Szekely, L, Kiseleva, E, Klein, G, Terenius, L, Wiman, K G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42958/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8278402/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.1.413
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