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p53 C-terminal interaction with DNA ends and gaps has opposing effect on specific DNA binding by the core

In addition to binding DNA in a sequence-specific manner, the p53 tumour suppressor protein can interact with damaged DNA. In order to understand which structural features in DNA the C-teminal domain recognises we have studied the interaction of p53 protein with different types of DNA oligonucleotid...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Zotchev, Sergey B., Protopopova, Marina, Selivanova, Galina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110788/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11024181/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.20.4005
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