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Eukaryotic ribonucleases HI and HII generate characteristic hydrolytic patterns on DNA–RNA hybrids: further evidence that mitochondrial RNase H is an RNase HII

RNase H activities from HeLa cells (either of cytoplasmic or mitochondrial origin), and from mitochondria of beef heart and Xenopus ovaries, have been tested with RNA–DNA substrates of defined length (20 bp) and sequence. Substrates were either blunt-ended, or presented DNA or RNA overhangs. The hyd...

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Dettagli Bibliografici
Autori principali: Pileur, Frédéric, Toulme, Jean-Jacques, Cazenave, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC110728/
https://ncbi.nlm.nih.gov/pubmed/10982891
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