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Eukaryotic ribonucleases HI and HII generate characteristic hydrolytic patterns on DNA–RNA hybrids: further evidence that mitochondrial RNase H is an RNase HII

RNase H activities from HeLa cells (either of cytoplasmic or mitochondrial origin), and from mitochondria of beef heart and Xenopus ovaries, have been tested with RNA–DNA substrates of defined length (20 bp) and sequence. Substrates were either blunt-ended, or presented DNA or RNA overhangs. The hyd...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Pileur, Frédéric, Toulme, Jean-Jacques, Cazenave, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110728/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10982891/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.18.3674
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