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The DNA ligase III zinc finger stimulates binding to DNA secondary structure and promotes end joining

The ability to rejoin broken chromosomes is fundamental to the maintenance of genetic integrity. Mammalian cells possess at least five DNA ligases, including three isoforms of DNA ligase III (Lig-3). Lig-3 proteins differ from other DNA ligases in the presence of an N-terminal zinc finger (Zn-f) mot...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Taylor, Richard M., Whitehouse, Claire J., Caldecott, Keith W.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110727/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10982876/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.18.3558
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