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The DNA ligase III zinc finger stimulates binding to DNA secondary structure and promotes end joining

The ability to rejoin broken chromosomes is fundamental to the maintenance of genetic integrity. Mammalian cells possess at least five DNA ligases, including three isoforms of DNA ligase III (Lig-3). Lig-3 proteins differ from other DNA ligases in the presence of an N-terminal zinc finger (Zn-f) mot...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Taylor, Richard M., Whitehouse, Claire J., Caldecott, Keith W.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110727/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10982876/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.18.3558
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