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The DNA ligase III zinc finger stimulates binding to DNA secondary structure and promotes end joining

The ability to rejoin broken chromosomes is fundamental to the maintenance of genetic integrity. Mammalian cells possess at least five DNA ligases, including three isoforms of DNA ligase III (Lig-3). Lig-3 proteins differ from other DNA ligases in the presence of an N-terminal zinc finger (Zn-f) mot...

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Bibliografske podrobnosti
Main Authors: Taylor, Richard M., Whitehouse, Claire J., Caldecott, Keith W.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC110727/
https://ncbi.nlm.nih.gov/pubmed/10982876
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