The DNA ligase III zinc finger stimulates binding to DNA secondary structure and promotes end joining

The ability to rejoin broken chromosomes is fundamental to the maintenance of genetic integrity. Mammalian cells possess at least five DNA ligases, including three isoforms of DNA ligase III (Lig-3). Lig-3 proteins differ from other DNA ligases in the presence of an N-terminal zinc finger (Zn-f) mot...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Taylor, Richard M., Whitehouse, Claire J., Caldecott, Keith W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2000
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110727/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10982876/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.18.3558
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