Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA
Werner syndrome (WS) is an autosomal recessive disease characterized by early onset of many features of aging, by an unusual spectrum of cancers, and by genomic instability. The WS protein (WRN) possesses 3′→5′ DNA helicase and associated ATPase activities, as well as 3′→5′ DNA exonuclease activity....
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110713/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10954593/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.17.3260 |
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