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NMR characterization of a kissing complex formed between the TAR RNA element of HIV-1 and a DNA aptamer

This work presents the first structural analysis of an RNA–DNA complex consisting of an 18 nt RNA hairpin and a 20 nt DNA aptamer. The DNA molecule was previously selected, from a randomly synthesized library, against the transactivation response element (TAR) involved in transcriptional regulation...

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Main Authors: Collin, D., van Heijenoort, C., Boiziau, C., Toulmé, J.-J., Guittet, E.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC110702/
https://ncbi.nlm.nih.gov/pubmed/10954609
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