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The Protein Tyrosine Kinase p56(lck) Is Required for Triggering NF-κB Activation upon Interaction of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein gp120 with Cell Surface CD4

We have previously shown that NF-κB nuclear translocation can be observed upon human immunodeficiency virus type 1 (HIV-1) binding to cells expressing the wild-type CD4 molecule, but not in cells expressing a truncated form of CD4 that lacks the cytoplasmic domain (M. Benkirane, K.-T. Jeang, and C....

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Bibliografiske detaljer
Main Authors: Briant, Laurence, Robert-Hebmann, Véronique, Acquaviva, Claire, Pelchen-Matthews, Annegret, Marsh, Mark, Devaux, Christian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110439/
https://ncbi.nlm.nih.gov/pubmed/9621091
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