A Third-Generation Lentivirus Vector with a Conditional Packaging System

Vectors derived from human immunodeficiency virus (HIV) are highly efficient vehicles for in vivo gene delivery. However, their biosafety is of major concern. Here we exploit the complexity of the HIV genome to provide lentivirus vectors with novel biosafety features. In addition to the structural g...

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Main Authors: Dull, Tom, Zufferey, Romain, Kelly, Michael, Mandel, R. J., Nguyen, Minh, Trono, Didier, Naldini, Luigi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Gene Therapy
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC110254/
https://ncbi.nlm.nih.gov/pubmed/9765382
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