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A Third-Generation Lentivirus Vector with a Conditional Packaging System

Vectors derived from human immunodeficiency virus (HIV) are highly efficient vehicles for in vivo gene delivery. However, their biosafety is of major concern. Here we exploit the complexity of the HIV genome to provide lentivirus vectors with novel biosafety features. In addition to the structural g...

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Autores principales: Dull, Tom, Zufferey, Romain, Kelly, Michael, Mandel, R. J., Nguyen, Minh, Trono, Didier, Naldini, Luigi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC110254/
https://ncbi.nlm.nih.gov/pubmed/9765382
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