A Third-Generation Lentivirus Vector with a Conditional Packaging System

Vectors derived from human immunodeficiency virus (HIV) are highly efficient vehicles for in vivo gene delivery. However, their biosafety is of major concern. Here we exploit the complexity of the HIV genome to provide lentivirus vectors with novel biosafety features. In addition to the structural g...

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Détails bibliographiques

Publié dans:	J Virol
Auteurs principaux:	Dull, Tom, Zufferey, Romain, Kelly, Michael, Mandel, R. J., Nguyen, Minh, Trono, Didier, Naldini, Luigi
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1998
Sujets:	Gene Therapy
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110254/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9765382/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.11.8463-8471.1998
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