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Development of a Self-Inactivating Lentivirus Vector

We have constructed a new series of lentivirus vectors based on human immunodeficiency virus type 1 (HIV-1) that can transduce nondividing cells. The U3 region of the 5′ long terminal repeat (LTR) in vector constructs was replaced with the cytomegalovirus (CMV) promoter, resulting in Tat-independent...

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Hlavní autoři: Miyoshi, Hiroyuki, Blömer, Ulrike, Takahashi, Masayo, Gage, Fred H., Verma, Inder M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC110156/
https://ncbi.nlm.nih.gov/pubmed/9733856
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