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Development of a Self-Inactivating Lentivirus Vector

We have constructed a new series of lentivirus vectors based on human immunodeficiency virus type 1 (HIV-1) that can transduce nondividing cells. The U3 region of the 5′ long terminal repeat (LTR) in vector constructs was replaced with the cytomegalovirus (CMV) promoter, resulting in Tat-independent...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Miyoshi, Hiroyuki, Blömer, Ulrike, Takahashi, Masayo, Gage, Fred H., Verma, Inder M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110156/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9733856/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.10.8150-8157.1998
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